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Bubble Formation in Helicoidal DNA Molecules

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dc.contributor.author Tabi, Conrad Bertrand
dc.date.accessioned 2018-07-12T13:15:47Z
dc.date.available 2018-07-12T13:15:47Z
dc.date.issued 2016-11
dc.identifier.citation J Phys Chem Biophys 2016, Vol 6(6): 230 en_US
dc.identifier.issn 2161-0398
dc.identifier.uri DOI: 10.4172/2161-0398.1000230
dc.identifier.uri http://hdl.handle.net/123456789/1867
dc.description.abstract Wave interaction is addressed the framework of the helicoidal Peyrard-Bishop model of DNA. The model is first reduced to a set of coupled nonlinear Schrodinger equations via the multiple scale expansion. Modulational instability analysis shows that multi-breather trains exist in large regions of instability, while trains of one-humped breathers are observed for the single excitation mode. Analytical solutions are proposed, where single modes are proposed to described DNA respiration and coupled waves rather describe the bubbles observed in experiments. These bubbles are shown to be more effective under weak helicoidal coupling. The process of strand separation is also discussed. PACS number(s): 87.14.E-, 87.15.H-, 05.45.Yv, 05.45.-a en_US
dc.language.iso en en_US
dc.subject DNA en_US
dc.subject Solitons en_US
dc.subject Transcription en_US
dc.subject Bubble formation en_US
dc.subject Base pairs en_US
dc.title Bubble Formation in Helicoidal DNA Molecules en_US
dc.type Article en_US


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