| dc.description.abstract |
Dyslipidemia is a highly prevalent condition, and includes a collection of diseases
that cause increased levels of plasma triglycerides and/or cholestrol, or
decreased levels of HDL-C, with a prototypical disease being familial hypercholesterolemia.
Dyslipidemic conditions promote increased atherogenesis
through the oxidation of lipids by macrophages, and an increased response to
injury by the vascular endothelium. This vascular damage, loss of vascular
compliance, and overall hardening of arteries lead to sequellae such as cardiovascular
disease, cerebrovascular events, and aneurysm formation. It has
been established that certain risk factors predispose individuals to the sequellae
of atherosclerosis, including smoking, diabetes, hypertension, and hyperlipidemia.
However, studies show that these risk factors can be seen in children
as well. This review aims to assess the effect of these risk factors and demonstrate
their effects through adolescence into adulthood |
en_US |
